UBI集團訊息

UBP Presents at Antibody Drug Development Conference Plans to submit Phase I Clinical Trial application in 2017 for UB-221, a third-generation anti-IgE monoclonal antibody drug

United Biopharma (UBP, 6471) was invited to 2016 Antibody Drug Development Conference sponsored by Taiwan antibody association and Level biotechnology Inc.  on October 12th. Dr. Jiun-Bo Chenrepresented UBP addressing the topic of third-generation anti-IgE monoclonal antibody (called UB-221) development trends, and described the competitive advantage and future development goal of UB-221. Experts in the antibody drug development industry and clinical fields including Dr. Tse-Wen Chang and Hugh Davis were also invited.  

UB-221, which is considered a third-generation anti-IgE monoclonal antibody drug. UB-221 contains the advantages of “neutralization of free-IgE” and “blockade of B cell-mediated IgE synthesis,”was co-invented by Xolair® inventor, Dr. Tse-Wen Chang, and his Ph.D. students, Dr. Jiun-Bo Chen and Dr. Yu-Yu Shiung, Several biological activity studies have shown that UB-221 has better affinity to IgE and superior pharmacological property than Xolair® and Anti-CεmX.

UBP licensed UB-221 from Academia Sinica in October 2014, and has fully engaged UB-221 in pharmacological studies. UBP has developed a stable and high-yield cell line and antibody production technology for UB-221. UB-221 pre-clinical drug development stage and can be applied in the treatment of IgE-mediated diseases including asthma, allergic rhinitis, atopic dermatitis, food allergy and chronic idiopathic urticarial. UB-221 shows strong market potential in the future.


About UBP (6471)
UBP was established in September 2013 as a spinoff from United Biomedical, Inc., Asia, and is strategically partnering with Formosa Plastics Group. UBP has an integrated monoclonal antibody drug development platform, and focuses on development, manufacturing, and marketing of innovative monoclonal antibody drugs and biosimilars. With a spirit of “innovation and practicality,” UBP is dedicated to addressing unmet medical needs of mankind. and For more information, please visit http://www.unitedbiopharma.com
 
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